Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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Garlic oil inhibits dextran sodium sulfate-induced ulcerative colitis in rats. Additionally our results provide novel evidence that A.

Amphipterygium adstringens – Wikipedia

Probability values of were considered to be significant. Therefore, the present study aimed to investigate the antioxidant, anti-inflammatory, and immunomodulatory activities of A. However, failures in immune defense or plaque control result in development of gingival inflammation [ 25 — 27 ].

In this regard, the use of alternative therapies has emerged as a common approach in gastrointestinal diseases; actually, studies describe that almost half of IBD patients have ever taken or currently use complementary remedies [ 56 ]. Strains were cultured following their specific requirements. The histological scores indicate that treatment with AaEE decreased mucosal damage characterized by loss of crypt glands and amphipteryggium destruction and inhibited colon shortening as observed in the DSS-alone group.

amphiptdrygium Mice were sacrificed using CO 2 chamber, and all efforts were made to minimize pain. Journal of Agricultural and Food Chemistry. There exists an increasing prevalence of infections worldwide, due to, among other reasons, the growing resistance of pathogens to antibiotics and antifungals as well as alterations in the autoimmune system.


Antioxidants and Redox Signaling. Experimental colitis models have been used to adstgingens therapeutic agents and elucidate the underlying physiologic mechanisms of UC. In this work, we evaluated the in vitro antimicrobial and antiproliferative activities of the methanolic extract of A. Chlorhexidine is the most common mouthwash product used for caries and periodontal diseases and kills bacteria by causing a precipitation or coagulation of the adstrnigens content.

Because of its ever-growing popularity and since the most sought after part of the plant is its bark, the cuachalalate was as of considered an endangered species. Journal of Nutritional Biochemistry. Effect of plants used in Mexican traditional medicine on Candida albicans biofilm.

The supernatant was collected ampuipterygium the biochemical estimations. Plant-based, traditional remedies are now being used as alternative therapeutic strategies. In this investigation, we tested the crude extract of A.

The findings of this study suggest that the extract of A. Total Phenolic Content The Folin-Ciocalteu method [ 22 ] was used to determine the total phenolic content of a 0. The results suggested the protective potential of AaEE in DSS-induced colitis and amphipteryguum might be attributed to its amphipterygiuj compounds that have been found to induce a wide spectrum of activities such as reduction in oxidative stress, suppression of inflammation, modulating numerous signal transduction pathways, and induction of apoptosis.


Principles of the bark of Amphipterygium adstringens (Julianaceae) with anti-inflammatory activity.

Its virulence relies on its ability to form biofilms on teeth surface, to degrade carbohydrates particularly refined sugars from food with the formation of large amounts of organic acids that demineralize tooth enamel, and to adapt and tolerate environmental stresses, particularly low pH aciduricity [ 29 ]. The sections were also stained with Alcian blue to evaluate the presence of goblet cells. The AaEE were orally administered for 10 days.

Journal List Mediators Inflamm v. As for activity of A. The weight loss, stool formation, and bloody stool scores were averaged to determine the DAI.

Methanol was used as the blank sample. The yield of AaEE was According to Al-Fatimi et al.

Amphipterygium adstringens

Trees and Shrubs of Mexico pt. The anthers, like the mature sepals, are also covered with long, fine hairs.

Animals from this group showed a variety of clinical symptoms of IBD including diarrhea, bloody stool, and weight loss. Competing Interests The authors declare that there are no competing interests. Although all of them have shown some grade of efficacy in these intestinal conditions, the frequency and severity of adverse effects, inconvenient dosing regimen, and partially prohibitive price limit their long-term use [ 34 ].