Cytology. Since the publication of the consensus guidelines, new cervical cancer screening guidelines have been published and new information has. ASCCP Guideline. HPV Unknown. HPV Positive*. Repeat Cytology. -. @ 12 mos. Cytology. @ 6 & 12 mos OR. HPV DNA Testing. @ 12 mos. ASC or HPV (+) —. Manage per. ASCCP Guideline. HPV Unknown. HPV Positive*. Repeat cytology. >> ASC or HPV (+) > Repeat Colposcopy. @ 12 mos cytology. @6& 12 mos OR.

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Dysplasia associated with atypical glandular cells on cervical cytology [published correction appears in Obstet Gynecol.

Update on ASCCP Consensus Guidelines for Abnormal Cervical Screening Tests and Cervical Histology

Colposcopy is also recommended when two consecutive Paps are unsatisfactory. New data have emerged since publication of the American Society for Colposcopy and Cervical Pathology’s consensus guidelines for management of abnormal cervical cytology and histology.

Clinical judgement is always appropriate. J Natl Cancer Inst. Baseline cytology, human papillomavirus testing, and risk for cervical neoplasia: The incidence of HSIL in adolescents is 0. See related handout on HPV and Pap testingwritten by the authors of this article. Updated guidelines published alvorithm October place greater emphasis on testing for high-risk human papillomavirus HPV.

How do I access the new guidelines? Cervical cytology of atypical squamous cells-cannot exclude high-grade squamous intraepithelial lesion ASC-H: Abnormal cervical cytology in pregnancy: Cytologic screening should be initiated three years after first intercourse, or at 21 years of age, whichever comes first.

Guidelines are intended for use only with HPV tests that have been analytically and clinically validated, as documented by Food and Drug Administration FDA licensing and approval or publication in peer-reviewed scientific literature Management based on results of HPV tests that have not been similarly validated may not result in outcomes intended by these guidelines and may increase the potential for patient harm.


Prevalence of and risks for cervical human papillomavirus infection and squamous intraepithelial lesions in adolescent girls: Endometrial cells are found on 0. Since publication of the American Society for Colposcopy and Cervical Pathology ASCCP consensus guidelines for management of abnormal cervical cytology 12 and histology, 34 new data have emerged. Therefore, women with abnormalities need more intensive follow-up.

Because the KPNC follow up of patients covers less than 10 years, more time will be needed to see if these women can return to routine asvcp after multiple negative follow-up tests.

Rate of pathology from atypical glandular cell Pap tests classified by the Bethesda nomenclature. These low-risk women are at high risk for HPV exposure and lesions, and should be observed. Choose a single article, issue, or full-access subscription. If satisfactory colposcopy does not identify CIN 2,3 aogorithm endocervical sampling is negative, management may include a diagnostic excisional procedure or cytology and colposcopy every six months until both are negative twice.

Consensus Guidelines FAQs – ASCCP

Management of cervical intraepithelial neoplasia during pregnancy with LOOP excision. High-grade squamous intraepithelial lesion. Low-grade squamous intraepithelial lesion. Should women with atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion, receive reflex human papillomavirus-DNA testing? Evaluating the endocervical canal for neoplasia by colposcopy or endocervical sampling.

Testing should be restricted to high-risk oncogenic HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and Therefore, if the initial cytology is AGC—favor neoplasia or AIS and no invasion is identified, an excisional procedure is still recommended. Thank you Your feedback has been sent. Arch Pediatr Adolesc Med. What should I do? Is conservative treatment for adenocarcinoma in situ of the cervix safe?


Genital human papillomavirus infection: Obtaining a specimen for histologic evaluation by endometrial biopsy, dilatation and curettage, or hysteroscopy.

ASCCP Mobile App – ASCCP

Algorithms are available at www. However, even with negative cytology, older women who are HPV positive have a greater risk of developing CIN 3 within 10 years, compared with alogrithm women If colposcopy is inadequate, diagnostic excision is recommended. More in Pubmed Citation Related Articles. Management of women with low-grade squamous intraepithelial lesion.

Updated Consensus Guidelines FAQs

How should I manage women with discordant cotesting results? CIN 3 is considered a cancer precursor. For women years of age, routine screening with cytology in 3 years is indicated.

How do I manage my patients? Conservative management of adolescents with any cytologic or histologic diagnosis except specified cervical intraepithelial neoplasia, grade 3 and adenocarcinoma in situ is recommended. This content is owned by the AAFP. HPV positivity has a high positive predictive value for significant cervical disease, with 20 percent of women having CIN 3 or cancer on biopsy.

Management of women with atypical squamous cells of undetermined significance.