Among the ameloblastomas, the desmoplastic variation is rare. The desmoplastic ameloblastoma (DA) is characterized by specific clinical, imaging, and. Desmoplastic ameloblastoma (DA) is a rare variant of ameloblastoma, and less than patients have been reported in the literature. The present case. Desmoplastic Ameloblastoma is a rare variant of ameloblastoma. 90 cases of desmoplastic ameloblastoma have been reported so far in literature. We are.
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Desmoplastkc tumor growth factor- TGF- expression has been reported in DA but not in conventional ameloblastomas [ 7 ], implying that TGF- plays a part in the formation of the desmoplastic matrix perhaps by modulating the extracellular matrix in the desmoplastic regions of DA [ 8 ].
Intra-oral periapical radiograph showing irregular radiolucencies with faint radio-opacities. None, Conflict of Interest: Ann Maxillofac Surg ;3: Based on ameloblawtoma clinical and radiographic appearance, a provisional diagnosis of odontogenic myxoma was made.
Desmoplastic Ameloblastoma: A Case Report
Our case was consistent with these common features reported in the literature. We report a case of desmoplastic ameloblastoma in a year-old female with dsemoplastic painless swelling in the left anterior maxillary region. Buccolingual expansion of the maxillary process was evident. Desmoplastic ameloblastoma DA is a rare variant of ameloblastoma AM.
Desmoplastic ameloblastoma Rastogi, R. The most striking feature which separates DA from conventional ameloblastoma is the presence of extensive stromal dsmoplastic with an abundance of thick collagen fibers which compress the odontogenic epithelial islands. Proper diagnosis is necessary to report such a case, so that the actual incidence can be noted. With limited understanding of its biologic behavior and prognosis, the proper treatment strategies for desmoplastic ameloblastoma are not entirely defined so far.
A previous study reports that DA tends to be less biologically aggressive than conventional ameloblastoma based on their estimated mean growth rates [ 5 ]. Int J Oral Maxillofac Surg ; Immunohistochemical profiling of ameloblastomas using cytokeratin, vimentin, smooth muscle actin, CD34 and S Report of a case and review of the literature. Gross picture of the resected area Click here to view.
The oxytalan fibers in the stromal tissue suggest that the tumor derived from the epithelial rest of Malassez in the periodontal membrane of a related tooth.
Sign up for our Email Newsletters. Approximately half of the desmoplastic lesions are located in the maxilla, and the vast majority of them occur in the anterior or premolar portion of the jaws. In addition, areas of cystic degeneration and squamous metaplasia were also seen Figure 5. How to cite this URL: Microcysts that contain eosinophilic amorphous deposits or appear empty may occur centrally.
Formation of metaplastic bone trabeculae osteoplasia rimmed by active osteoblasts has been described in a few cases. Desmoplastic ameloblastoma of the mandible: The intraoral examination disclosed a large mass, approximately 4.
There was loss of lamina dura around the involved teeth. His past medical history was noncontributory.
Desmoplastic ameloblastoma with osteoplasia: Review of literature with a case report
WHO classifies ameloblastoma into four variants: Received Jan 26; Accepted Apr The present case is a hybrid ameloblastoma composed of areas of DA and follicular ameloblastoma. Desmoplastic desmoppastic in the mandible. This tumor is more commonly seen in the anterior region of jaws as a mixed radiopaque-radiolucent lesion resembling benign fibro-osseous lesions. Biological profile based on cases from the literature and own files.
This is an open-access article distributed under the terms of the Creative Ameloblaastoma Attribution-Noncommercial-Share Alike 3.
Desmoplastic variant of ameloblastoma: However, age and sex distribution do not differ from the other types of ameloblastoma. Unknown and somewhat controversial, but leading hypotheses include remnants of dental lamina, basal layer of oral mucosa and, less commonly, arising within pre-existing dentigerous cyst.
The mean age at initial presentation is J Craniofac Surg ; Odontogenic Tumors and Allied Lesions. Intraoral periapical radiograph shows an ill-defined multilocular lesion with loss of periodontal ligament space and displacement of lateral incisor a ; maxillary occlusal radiograph showing multilocular appearance and buccal cortical expansion b.
Un raro caso clinico]. This implies that the majority of conventional ameloblastomas are actually desmoplastic variants. A case report and literature review. Whether the recurrence is due to the nature of the tumor or due to the incomplete surgery remains speculative.
The columnar cells with reversed nuclear polarity are rarely conspicuous.
Case Reports in Pathology
Clinically, ameloblastoma is known to occur in three forms: Desmoplastic ameloblastoma of the mandible: These expressions might contribute to the distinct characteristics of DA. J Oral Maxillofac Surg. Effiom OA, Odukoya O.